Clinical Chemistry

Synopsis

Front Cover; Student Pin Code Page; Clinical Chemistry; Copyright Page; Table Of Contents; Preface; Further Reading; 1 An Introduction To Biochemistry And Cell Biology; Units And Measurements; Analytical Techniques; Ions And Molecules Of Biological Importance; Elements Of Cell Biology; Transport Mechanisms; 2 Biochemical Investigations In Clinical Medicine; Introduction; Use Of Biochemical Investigations; Diagnosis; Prognosis; Monitoring; Screening; Specimen Collection; The Test Request; The Patient; The Specimen; Urgent Requests; Repeat Requesting; Sample Analysis And Reporting Of Results Analysisreporting Results; Point-of-care Testing; Sources Of Error; Interpretation Of Results; Is It Normal?; Is It Different?; The Clinical Utility Of Laboratory Investigations; Specificity And Sensitivity; Efficiency; Predictive Values; Likelihood Ratios; Evidence-based Clinical Biochemistry; Clinical Audit; Screening; 3 Water, Sodium And Potassium; Introduction; Water Distribution; Sodium Distribution; Potassium Distribution; Water And Sodium Homoeostasis; Water And Extracellular Fluid Osmolality; Sodium And Extracellular Fluid Volume; Water And Sodium Depletion; Water Depletion Sodium Depletionwater And Sodium Excess; Water Excess; Sodium Excess; Laboratory Assessment Of Water And Sodium Status; Sodium Measurement; Measurement Of Osmolality; Measurement Of Anions (bicarbonate And Chloride); Hyponatraemia; Causes; Sodium Depletion; Water Excess; Combined Water And Sodium Excess; Other Causes Of Hyponatraemia; The 'sick Cell Syndrome'; Investigation Of Hyponatraemia; Management Of Hyponatraemia; Hypernatraemia; Potassium Homoeostasis; Potassium Depletion And Hypokalaemia; Clinical Features; Management; Potassium Excess And Hyperkalaemia; Clinical Features; Management 4 Hydrogen Ion Homoeostasis And Blood Gasesintroduction; Buffering Of Hydrogen Ions; Bicarbonate Reabsorption And Hydrogen Ion Excretion; Transport Of Carbon Dioxide; Clinical And Laboratory Assessment Of Hydrogen Ion Status; Disorders Of Hydrogen Ion Homoeostasis; Non-respiratory (metabolic) Acidosis; Increased Production Of Hydrogen Ions; Decreased Excretion Of Hydrogen Ions; Loss Of Bicarbonate; Excessive Infusion Of 'normal' (0.9%) Saline; The Anion Gap; Management; Respiratory Acidosis; Management; Non-respiratory (metabolic) Alkalosis; Management; Respiratory Alkalosis; Management Interpretation Of Acid-base Dataoxygen Transport And Its Disorders; Respiratory Failure And Respiratory Support; 5 The Kidneys; Introduction; The Biochemical Investigation Of Kidney Function; Measurement Of Glomerular Filtration Rate; Clearance; Plasma Creatinine; Plasma Urea; Cystatin C; Estimated Glomerular Filtration Rate; Assessment Of Glomerular Integrity; Tests Of Renal Tubular Function; Imaging And Renal Biopsy; Renal Disorders; Acute Kidney Injury; Pre-renal Acute Kidney Injury; Intrinsic Acute Kidney Injury; Causes And Pathogenesis.; Metabolic Consequences.; Natural History. William J. Marshall, Andrew Day, Marta Lapsley. Post-renal Acute Kidney Injury Includes Bibliographical References And Index.